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华大基因开盘跌停 股价报92.30元

发布于:2018-10-30 16:13

因主业无创DNA检测受质疑,基因测序上市公司华大基因(300676)股价在7月16日开盘即跌停。截至发稿,股价报92.30元。
 
Shares of Huada Gene (300676), a genetic sequencing company, fell to a halt at the start of trading on July 16, as noninvasive DNA testing was questioned. As of press time, the stock price was quoted at 92.30 yuan.
 
 
 
7月13日,虎嗅刊发头条文章《华大癌变》,报道了去年在湖南省长沙市望城区妇幼保健院诞生了一名“13号染色体长臂缺失综合症”男婴,认为该男婴的不幸降临和当时负责产检的医院和提供无创DNA检查的华大基因有关。
 
On July 13, the article "Huada Cancer Change" published in the headline of the Tiger Smell magazine reported the birth of a baby boy with "Chromosome 13 Long Arm Deletion Syndrome" in Wangcheng District Maternal and Child Health Hospital of Changsha City, Hunan Province, last year. It was believed that the boy's unfortunate arrival was related to the hospital in charge of maternity examination at that time and Huada gene which provided non-invasive DNA examination.
 
 
 
 
 
7月13日晚间,华大基因曾发布澄清公告。7月15日晚间,华大基因在其官网发布《华大基因致孕妈妈们的一封信》,欲再度减小此事件带来的影响。华大基因称,近期媒体报道的新闻,可能引起了诸位的担忧,将对湖南的这个案例作详细的说明。
 
On the evening of July 13th, the Chinese big gene had issued a Clarification Announcement. On the evening of July 15, Huada Gene released a letter to pregnant mothers on its official website in an attempt to reduce the impact of the incident once again. Huada Gene said that recent media reports may arouse your concern, and will give a detailed account of the case in Hunan.
 
 
 
华大基因指出,根据国家卫健委数据,目前已知出生缺陷病种超过8000种,中国出生缺陷发生率在5.6%左右。根据中华医学会发布的《孕前和孕期保健指南(2018版)》,在怀孕期间,每一名孕妈妈会进行7-11次不同项目的产前检查。目前的无创产前基因检测仅是其中的一项,针对21、18和13号染色体数目是否异常。
 
According to the National Health and Health Commission, more than 8,000 birth defects are known, and the incidence of birth defects in China is about 5.6%, according to Huada Gene. According to the Prenatal and Prenatal Health Care Guidelines (2018 edition) issued by the Chinese Medical Association, each pregnant mother will undergo 7-11 different prenatal examinations during pregnancy. Currently, non-invasive prenatal genetic testing is only one of them, aiming at whether chromosome 21, 18 and 13 are abnormal.
 
 
 
华大基因认为,上述男婴案例尚不在 “无创产前基因检测”的检测范围内。
 
According to the Chinese gene, the case of the baby boy is not in the detection range of "noninvasive prenatal genetic testing".
 
 
 
值得注意的是,除产品检测范围外,华大基因此次还否认了《华大癌变》一文中对当事人母亲关于产前咨询医生的一些说辞。
 
It is noteworthy that, in addition to the scope of product testing, Huada Gene also denied the "Huada Cancer" article on the mother of the party concerned about prenatal counseling doctor some of the remarks.
 
 
 
《华大癌变》文中提到,孕妇曾有过不良孕产史,因此特意要求医生做“更加全面准确的检查”,而望城妇幼的A医生建议不需要再做唐筛,直接做华大基因提供的“无创DNA检查”,并告知此检查全面、先进,“准确率高达99.99%”。最终结果显示“低风险”,医生认为没有异常。
 
"Huada Cancer" article mentioned that pregnant women had a history of adverse pregnancy and childbirth, so specially asked doctors to do "more comprehensive and accurate examination", and Wangcheng Maternal and Child's doctor A recommended no need to do Tang screen, directly do Huada Gene provided by the "non-invasive DNA test," and told the test is comprehensive and advanced, "the accuracy rate is as high as 99.99%. "." The final result showed "low risk", and doctors thought there was no abnormality.
 
 
 
产妇在省级医院做四维彩超时,发现胎儿发育迟缓等异常,市级医院的B医生本打算建议产妇做穿刺检查,当得知无创检查低风险后,便认为“问题应该不大”,并嘱咐产妇三周后复查B超。
 
Maternal in the provincial hospital to do four-dimensional color Doppler ultrasound, found fetal growth retardation and other abnormalities, municipal hospital B doctor intended to recommend puncture examination, when the knowledge of low-risk non-invasive examination, they thought that "the problem should not be too big", and asked the maternal three weeks later to review B ultrasound.
 
 
 
三周后,产妇在望城妇幼复查B超时,仍然显示胎儿多项指标异常。A医生在结合无创低危的结果后,认为风险不大,只是医嘱“加强营养,注意胎动”。期间,产妇还在望城妇幼咨询过某医学教授C,教授得知无创低风险后,同样告知:问题不大,胎儿的异常“一般情况都会长好”。
 
Three weeks later, when the maternal and child were examined by B ultrasound in Wangcheng, the fetus still showed many abnormalities. Doctor A, after combining the results of non-invasive low-risk, considered that the risk was small, but the doctor ordered "strengthen nutrition, pay attention to fetal movement". During the period, maternal and child counseling in Wangcheng a medical professor C, the professor learned that the low-risk non-invasive, the same inform: the problem is not big, fetal abnormalities "will grow well in general".
 
 
 
最终,孕妇放弃了可作为产前诊断的羊水穿刺。
 
Eventually, the pregnant woman gave up the amniocentesis for prenatal diagnosis.
 
 
 
华大基因在公开信中则否认上述曲折,称该案例通过超声检查已经发现异常,如通过做穿刺的产前诊断是可以有效避免的,当事医生也给出了进行脐带血穿刺的建议,但该名孕妈妈自行放弃了确诊的机会。
 
In an open letter, Huada denied the twists and turns, saying the case had been detected by ultrasound, such as prenatal diagnosis through puncture can be effectively avoided, the doctor also gave advice for umbilical cord blood puncture, but the pregnant mother gave up the opportunity to make a definite diagnosis.
 
 
 
华大基因强调并不存在媒体所说的“三位医生接连误判”。
 
The Chinese gene emphasizes that there is no "three doctors' miscarriage of justice" in the media.
 
 
 
公开信提醒,无创产前基因检测虽然具有高准确性的特点,目前已被多个国家推荐作为筛查技术,但仍然具有一定技术局限性和适用范围,存在一定漏检的概率(假阴)。
 
Open letter reminded that although non-invasive prenatal genetic testing has high accuracy characteristics, has been recommended as a screening technology by many countries, but still has certain technical limitations and scope of application, there is a certain probability of missed detection (false negative).
 
 
 
华大基因提供的数据显示,截至2018年5月31日,华大基因为全球313万余名孕妇提供了无创产前基因检测,约1.9万孕妇因该项技术提早发现了胎儿21、18、13号染色体数目异常并采取了预防措施。
 
Huada Gene has provided noninvasive prenatal genetic testing for more than 3.13 million pregnant women worldwide as of May 31, 2008. About 19,000 pregnant women have found chromosome 21, 18 and 13 abnormalities in their fetuses and taken preventive measures.
 
 
 
目前已出生248万名宝宝中,已确染色体数目异常证的有70名,即大约每3.5万个检测会出现1个这样的情况。
 
Of the 2.48 million babies born, 70 have confirmed abnormal chromosome numbers, or about one for every 35,000 tests.
 
 
 
华大基因称,为保障受检者,已为每一位受检的孕妈妈都购买了基因检测医疗保险,出现上述情况就会给予赔付。
 
Huada Gene said it had purchased genetic testing medical insurance for every pregnant mother in order to protect the recipients, and would pay for the above.

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